BRCA1 and breast cancer: The incidence of BC in our cohort was slightly higher than that reported in previous studies, such as that described by Vencken et al. [4], who identified 8 primary BCs in 79 BRCA1/2-OC women (10.1%) during a mean period of 6.7 years, and by Domchek et al. [5], who reported 11% of BCs (18 patients) in a group of 164 during a mean follow-up of 5.8 years.