HTHQ at a dose of 50 mg/kg was also more effective than rasagiline regarding serum 8-isoprostane concentration (p < 0.05), DC content in the brain (p < 0.05) and serum (p < 0.05), and OMP levels in the brain (p < 0.01) and serum (p < 0.01) of rats with PD. This evidence concerns the gene OMP and Parkinson disease.