IGHE and atopic eczema: Another study on the effect of PLE in atopic dermatitis assessed its clinical therapeutic effect in NC/Nga mice, showing that oral administration of PLE for 4 weeks into the atopic dermatitis mouse model with overt dermatitis resulted in dose‐dependent decreases in not only the skin severity score but also in transepidermal water loss (TEWL), serum IgE, and skin scratching behavior.5