In contrast to the reduced levels of these proteins on the cell surface of the infected cells, no effect on the mRNA levels of MICA, MICB, ULBP2, and ULBP3 was observed following infection (Figure 3B), or on the mRNA levels of CRT and ERp57 (Figure S2G), indicating that the impaired expression of MICA, MICB, ULBP2, and ULBP3 in reovirus-infected cells was not due to reduced transcription levels of these NKG2D ligands. This evidence concerns the gene PDIA3 and infection.