Interrogation of the Chinese Glioma Genome Atlas (CGGA; data set: mRNAseq_693) (CGGA is included in GlioVis) showed that GBM patients with isocitrate dehydrogenase (IDH) mutations express lower FBXW7 mRNA levels as compared with GBM patients with wild-type (WT) IDH (***p=0.00086) (Figure 5B). Here, IDH3A is linked to central nervous system cancer.