EWSR1 and neoplasm: For example, EWS-FLI1 stimulates the expression of c-Myc (Dauphinot et al., 2001), Gli1 (Glioma-associated Oncogene Homolog 1) (Merchant et al., 2009; Mullard et al., 2020) or NR0B1 (Nuclear Receptor subfamily 0 group B member 1) (Kinsey et al., 2006; Gangwal et al., 2008), genes involved in tumor progression and metastatic development.