Moreover, LYS fibrils can readily cross cell membrane via various mechanisms.[26] In addition, LYS fibrils have well‐documented anti‐cancer, antibacterial characteristics.[27, 28] In neuroblastoma, the lysozyme fibrils achieve anti‐cancer effect by inducing cell death via different mechanisms involving apoptotic and necrotic pathways.[28] Because of these superior characteristics of LYS fibrils, it was chosen as the main nanocarrier candidate for siRNA delivery in this study. This evidence concerns the gene LYZ and cancer.