Contrary, expression of the gene encoding for patatin‐like phospholipase domain‐containing 2 (PNPLA2, ATGL) involved in TAG catabolism[14] was downregulated in BOLD‐100‐resistant cells, supporting a lipid anabolic rather than catabolic resistance‐associated phenotype in the CRC model. This evidence concerns the gene PNPLA2 and colorectal carcinoma.