The anatomical distribution of meningiomas differed between NF2 patients and sporadic case with NF2 alterations, especially in the frequency of the falx meningiomas (22.0% in meningiomas of NF2 patients, 8.4% in sporadic NF2-altered tumours, p = 2.2 × 10–16) (Table 1). This evidence concerns the gene NF2 and meningioma.