NF2 and neoplasm: Consistent with these data, GSEA analysis using single-cell data (C8: cell type signature gene set) showed that the differentially expressed genes in NF2 patients compared to sporadic NF2-altered tumours were significantly overrepresented in signatures associated with ‘DESCARTES FETAL INTESTINE MYELOID CELLS’ (FDR q-value < 0.001), ‘DESCARTES FETAL CEREBELLUM MICROGLIA’ (FDR q-value < 0.001), and ‘CUI DEVELOPING HEART C8 MACROPHAGE’ (FDR q-value < 0.001) (Additional file 1: Figure S7, Additional file 2: Table S6).