IHC staining supported the findings from mRNA sequencing results, identifying more abundant CD45+ leukocytes (3.0% ± 1.7/TCC, p = 0.006) (Fig. 4A), CD68+ macrophages (2.8% ± 1.7 /TCC, p = 0.007) (Fig. 4B), and CD68+163− macrophages in meningiomas with NF2 patients (1.3% ± 0.9/TCC, p = 0.004) (Fig. 4D) infiltrated in NF2 patients than sporadic NF2-altered meningiomas. The gene discussed is CD68; the disease is meningioma.