The other patient was a 78-year-old male and at baseline his Hb was 56 g/L, 3 months postoperatively his Hb was 124 g/L, and his Hb was 81 g/L at 5 year follow-up.In this patient, fixed without mesh, and he was complicated with chronic obstructive pulmonary disease, Liver cirrhosis, Personal history of bladder cancer. The gene discussed is GSTM1; the disease is cirrhosis of liver.