In models adjusted for demographic parameters, kidney-related factors, inflammation, ESA use, and mineral metabolism parameters, anemia was significantly associated with higher total FGF23 values (standardized β (95% confidence interval (CI)) 0.10 (0.04, 0.17), p = 0.002, n = 459 in the fully adjusted model; Table 5, Supplemental Table 4). The gene discussed is FGF23; the disease is anemia.