PDGFRA and Corneal astigmatism: In the GWAS meta-analysis with Asian (Chinese, Malay, and Indian living in Singapore) ancestry cohorts (n = 8513) by Fan et al., the PDGFRA intronic SNP, rs7677751, showed the strongest association with corneal astigmatism, and its minor allele T was associated with an increased risk (OR = 1.26) of the disease in the cases with corneal astigmatism ≤  − 0.75 D9.