PDGFRA and Corneal astigmatism: In addition, recent large-scale GWASs of corneal astigmatism with European and/or Asian ancestry cohorts provided strong evidence of association between corneal astigmatism and PDGFRA SNPs (lead SNPs: rs7673984 or rs4864857)11,12, suggesting that PDGFRA plays a key role in the development of corneal astigmatism through genetic polymorphisms.