PDGFRA and Corneal astigmatism: The PDGFRA SNPs were not significantly associated with the cases with corneal astigmatism ≤  − 0.75 D. However, the odds ratios (ORs) of the minor alleles of SNPs in the upstream region of PDGFRA, including rs7673984, rs4864857, and rs11133315, tended to increase according to the degree of corneal astigmatism, and these SNPs were significantly associated with the cases with corneal astigmatism ≤  − 1.25 D or ≤  − 1.50 D (Pc < 0.05, OR = 1.34–1.39).