Circular RNAs (circRNAs) can exert similar regulatory roles in this context, as in the case of circEHBP1, which reportedly favors bladder cancer-associated lymphangiogenesis through the miR-130a-3p/TGFβR1/VEGF-D signaling axis.71 Meanwhile, circNFIB1 (hsa_circ_0086375) can inhibit lymphangiogenesis and LNM via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer.72 This evidence concerns the gene VEGFC and urinary bladder carcinoma.