Quantitative PCR (qPCR) confirmed a significant increase of mRNA expression for the chemokine ligands Cxcl10 and Cxcl11 (Fig. 8E), supporting our hypothesis that PARP14 inhibition enhances IFNγ signalling in tumour cells and upregulates immune cell infiltration into tumours. The gene discussed is PARP14; the disease is neoplasm.