IFNG and neoplasm: Despite PARP14 induction in tumours derived from IFNγ-naïve YUMM2.1 cells not depending on α-PD-1 treatment, we found by qPCR analysis that Ifng, Stat1 and other IFNγ target genes, including Parp14, were significantly increased in tumours that regrew following α-PD-1 treatment compared to control tumours (Fig. 9A).