CD8A and neoplasm: In addition, whereas the α-PD-1-responding tumours had a variable level of different immune subsets scores, relapsing tumours had a significantly lower score of macrophage and naïve CD8 T cell, which might suggest that α-PD-1 responding tumours had fewer differentiated or functional innate and adaptive immune cells in the tumour microenvironment (Fig. 9J, K).