To reveal a better understanding of the mechanism by which ferroptosis is induced by IKE + DHAA in GBM and PCa cells, we performed a detailed analysis of GPX4 levels in both cell models and determined that DHAA alone and IKE + DHAA induced a decrease in GPX4 levels in GBM and PCa cells (Fig. 4a, b, c). The gene discussed is GPX4; the disease is glioblastoma.