The ChIP-qPCR and electrophoresis of NHGFs and patient gingival tumor fibroblasts confirmed that ZNF513 in these cells had clear binding at the enrichment peak of the SOS1 promoter region (Fig. 7a, b), and the binding sequence was confirmed to be the genomic sequence of SOS1 (Supplementary Fig. 6f). Here, ZNF513 is linked to gingival neoplasm.