In the patient’s primary gingival tumor fibroblasts, we found that the increased expression of KIF3C or ZNF513 was consistent with the KIF3C or ZNF513 expression in patient’s gingival tumor tissues (Supplementary Fig. 2b), and tumor fibroblasts had a stronger ability to proliferate and migrate after 24 h cultured compared with NHGFs (Fig. 3h, i; Supplementary Fig. 3a, d; Supplementary Fig. 4b). The gene discussed is ZNF513; the disease is gingival neoplasm.