rs148726219 is located within intron 2 of the FOSB gene (ENST00000353609.8), a member of the AP-1 complex which has an exceptionally stable splice isoform (ΔFOSB, ENST00000615753.4, ENST00000592436.5) that has been previously implicated in addiction, epilepsy, and cognition [27–29]. The gene discussed is FOSB; the disease is epilepsy.