On the other hand, PAI-1 levels were significantly higher in IBD patients with endoscopic [Figure 1C] or clinical activity [Figure 1D] compared with inactive and control patients [endoscopically active vs inactive: 27.77 vs 21.67 ng/mL, p = 0.0018, endoscopically active vs control: 27.77 vs 24.62 ng/mL, p = 0.0239; clinically active vs inactive: 27.44 vs 21.7 ng/mL, p = 0.0069, clinically active vs control: 27.44 vs 24.62 ng/mL p = 0.0273]. This evidence concerns the gene SERPINE1 and inflammatory bowel disease.