To our knowledge, this is the first study to investigate DMF for myogenic disease, and our molecular data indicate dystrophic skeletal muscle uptake and pharmacodynamic action (e.g., 50% increase in NQO1, unchanged HO-1) as biomarked previously in the context of rheumatoid arthritis (30% increase in NQO1, unchanged HO-1) and RRMS (15% increase in NQO1, unchanged HO-1) (12). The gene discussed is HMOX1; the disease is rheumatoid arthritis.