Mutations of Nr2f1 are highly related to neurodevelopmental disorders (NDDs), such as intellectual disability (ID) and autism spectrum disorders (ASD) (Bertacchi et al., 2020; Bosch et al., 2014; Contesse et al., 2019), and mutations of the Nr2f2 gene are associated with congenital heart defects (CHDs) (Al Turki et al., 2014). The gene discussed is NR2F1; the disease is neurodevelopmental disorder.