FGFR1 amplification also plays a role in ovarian cancer,163 bladder cancer,59 renal cell carcinoma,164 prostate cancer,165, 166 esophageal carcinoma,167 gastric cancer,168 colorectal cancer,169 pancreatic cancer,63, 170 head and neck squamous cell carcinoma,62, 171 and osteosarcoma.172. This evidence concerns the gene FGFR1 and head and neck squamous cell carcinoma.