FGFR1 and Familial prostate cancer: FGFR1 amplification also plays a role in ovarian cancer,163 bladder cancer,59 renal cell carcinoma,164 prostate cancer,165, 166 esophageal carcinoma,167 gastric cancer,168 colorectal cancer,169 pancreatic cancer,63, 170 head and neck squamous cell carcinoma,62, 171 and osteosarcoma.172