To detect whether the ROR2 expression is altered in Tetralogy of Fallot patients: The expression of ROR2 was detected by the immunohistochemistry (IHC), and the analysis revealed that the expression of ROR2 was significantly decreased in the TOF patients compared to the control group (Figure 1A,B, p < 0.0001). Here, ROR2 is linked to Tetralogy of Fallot.