To date, there is only one mouse model addressing the effects of individual p53 deficiency in EC development.[19] Mice with endometrium‐specific deletion of p53 developed carcinomas representing all type II histological subtypes, including serous, clear cell, undifferentiated EEC and UCS.[19] However, other studies in which p53 has been deleted along with other tumor suppressor genes have also shown that loss of p53 alone is not sufficient to cause EC. The gene discussed is TP53; the disease is carcinoma.