The cause of premature death of Pten‐deficient mice was previously described.[22] In case of double Pten/p53 double knock‐out, we performed a gross histopathological study that revealed proliferative lesions in multiple organs such as colon adenomas, hepatocellular dysplasia, severe thyroid hyperplasia, or lymphoma (Figure S2, Supporting Information), thus limiting the study of double Pten and p53 deletion in EC. This evidence concerns the gene PTEN and colon adenoma.