A brief description of previous works regarding niosomes are: Abtahi et al. loaded curcumin and miR-34a simultaneously in niosomes and used them for tumor inhibition [64]; by Tanovo et al., transferrin, folic acid-conjugated doxorubicin, and curcumin-loaded niosomes were developed for delivery in breast cancer [65]; Maurer et al. The gene discussed is TF; the disease is breast carcinoma.