As the positron range for [64Cu]Cu (1mm) is shorter than for [68Ga]Ga (4mm), a [64Cu]Cu-labeled uPAR-PET tracer, like [64Cu]Cu-DOTA-AE105, may enhance detection of smaller tumor volumes as previously demonstrated by us in a head to head comparison of [68Ga]Ga- and [64Cu]Cu-labeled radiotracers targeting the somatostatin receptors in neuroendocrine tumors [23]. Here, PLAUR is linked to neuroendocrine neoplasm.