On the other hand, regardless of being in the non-general obesity, the overweight, or the general obesity subgroup, the levels of ALT, ALP, and GGT, as well as the prevalence of abnormal ALT and GGT in the metabolically unhealthy subgroup were higher than that in metabolically healthy subgroup (all Pb < 0.05). The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.