With the non-general obesity subgroup as a reference, the levels of ALT, AST, ALP, and GGT in the general obesity subgroup increased by 26.2% (24.0%, 28.4%), 3.4% (1.8%, 5.0%), 10.0% (8.5%, 11.5%), and 34.7% (32.0%, 37.3%), respectively. The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.