ABCB6 and colorectal carcinoma: In parallel with the results of CRC cell line, ABC variants recognized in our tumor tissues were enriched among TF binding sites and active epigenetic makers such as H3K27ac, H3K4me1, ATAC peaks and DNaseI hypersensitive sites (DHSs) (all of P < 0.05, Fig. 3h and Fig. S6).