THBS1 and neoplasm: EPCAM-GFP+ BM-derived cells, that accounted for 21.2 ± 5.1% of the total cell population in tumors (Supplementary Fig. 8d), had the highest expression of Thbs1 and Vcan compared to that in EPCAM+ tumor epithelium or EPCAM-GFP- residential stromal cells and also compared to that in MTO or MC38 cells (Fig. 6d, e and Supplementary Fig. 8e).