At the end of study, the body weights of Aldh2 KI, HE and WT mice were 41.66 ± 1.40, 41.65 ± 1.13, and 36.95 ± 0.96 g respectively (Fig. 1a, P-for-trend = 0.0096). Here, ALDH2 is linked to hereditary elliptocytosis.