MAPT and Alzheimer disease: Within visual read tau-positive participants with AD, higher temporal meta-ROI SUVr was associated with worse cross-sectional performance on the MMSE (β = −0.29, CI −0.50 to −0.09, p = 0.008) and worse prospective decline on the MMSE (β = −0.14, CI −0.20 to −0.08, p < 0.001) (Figure 5C).