IFNB1 and colorectal adenocarcinoma: We used Caco-2 cells (i.e., human epithelial colorectal adenocarcinoma cell line) because they represent a more physiological system to study SARS-CoV-2 infection cycle, as opposed to the VERO cells (an African green Monkey kidney epithelial cell line), which do not produce alpha or beta interferons upon infection.