Here we also found that NQO1 was downregulated in IFN-γ or MDS/AML plasma treated or co-cultured BMMSCs (only with KG1a-TWIST1) and upregulated in BMMSCs treated with fludarabine or cocultured with KG1a-ko-TWIST1 (Fig. 6A–C). Here, NQO1 is linked to acute myeloid leukemia.