To address the mechanism by which nuclear TIAM1 promotes migration of NSCLC cells, we performed two proteomic screens to identify interactors of nuclear TIAM1: immunoprecipitation of TIAM1 from the nucleus of NSCLC cells and a BioID (proximity-dependent biotin identification) screen, both followed by mass spectrometry (SI Appendix, Fig. S4A). Here, TIAM1 is linked to non-small cell lung carcinoma.