MYC and intrahepatic cholangiocarcinoma: However, this has subsequently been split into two distinct categories (1) HGBL with MYC and BCL2 rearrangements, which account for 80–90% of such cases; and (2) HGBL with MYC and BCL6 rearrangements, which account for 10–20% of such cases, with substantial evidence allowing the former to be retained as a bona fide entity, while the latter seems to be more heterogeneous and has been relegated, by the ICC but not WHO, to a provisional entity [41].