APC and colorectal carcinoma: Here we aim to study the role of gut viruses using a mouse model of H. pylori-promoted CRC.12 We used shotgun viral metagenomic sequencing to characterize the viral community composition of the cecum, stool and intestinal samples from i) Apc+/1638N and ii) C57BL/6 mice, with and without H. pylori infection, as well as at different time points (before the onset of colonic tumors and afterward).