LS, hepatic echo, splenomegaly, GP73, total bilirubin, prothrombin time, prothrombin time activity and INR in the cirrhosis group were higher than those in the non-cirrhosis group, while ALB, PLT count and complement C4 in the cirrhosis group were lower than those in the non-cirrhosis group. The gene discussed is ALB; the disease is Cirrhosis.