Xu et al,[30] utilizing male C57/B6J mice, found that Shenfu injection up-regulated the expression of B-cell lymphoma-2 (Bcl-2) protein, thereby inhibiting myocardial apoptosis and mitigating mitochondrial damage induced by septicemia through downregulation of BH3 interacting domain death agonist and caspase-9 proteins. The gene discussed is CASP9; the disease is Sepsis.