BRAF and metastatic malignant neoplasm in the lymph nodes: A meta-analysis of 33 studies revealed that among 8838 patients, 5043 (57.1%) had BRAF V600E mutations, and these patients exhibited a higher risk of multifocality, extrathyroidal extension, lymph node metastasis, and disease recurrence.[37] However, the study included diverse ethnic groups, resulting in genetic background variations.