TNF and obstructive sleep apnea syndrome: IL-10 is secreted by activated T cells (mainly Treg cells, Th2 cells), lymphocytes, monocytes/macrophages, mast cells, etc. It is an anti-inflammatory factor that inhibits the pro-inflammatory factors TNF-α, IL-6, IL-8, etc.[49] Leon-Cabrera et al[12] showed that the severity of OSAHS was related to the concentration of anti-inflammatory factors, and the concentration of IL-10 decreased with the increase in Apnea–Hypopnea Index (AHI).