Similarly, serum IL-10 concentrations in patients with OSAHS were not statistically different between OSAHS patients and controls in case-control and cohort studies (SMD = 0.07, 95% CI = −0.61 to 0.75, P = .838; SMD = 0.49, 95% CI = −0.57 to 1.56, P = .591, Table 3). This evidence concerns the gene IL10 and obstructive sleep apnea syndrome.