CXCR5 and cancer: T follicular helper cells are characterized by the expression of the C-X-C motif chemokine receptor 5 (CXCR5) membrane marker and the receptor of chemokine (C-X-C motif) ligand 13 (CXCL13), which are required for their migration to the germinal center.[65,66] CXCL13/CXCR5 plays a major role in cancer cell growth.