Knockout of DANCR can delay the progression and initiation of hepatocellular carcinoma in an in situ hepatoma mouse model of patient-derived xenograft.[56] MIR4435-2 host gene has previously been reported as an oncogene in hepatocellular carcinoma and can promote the proliferation of cancer cells by upregulating miRNA-487a and UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5.[57,58]. This evidence concerns the gene DANCR and hepatocellular carcinoma.