No statistical association between VDR Bsm I polymorphism and sepsis susceptibility were observed under the allelic contrast model (B vs b, P = .11, OR = 0.67, 95% CI = 0.42–1.09), dominant genetic model (BB vs Bb + bb, P = .17, OR = 0.49, 95% CI = 0.18–1.36). This evidence concerns the gene VDR and Sepsis.