Possibly, curative approaches may eliminate the tumor cells, reducing the potential detrimental impact of KIAA1522-overexpressed cells, or KIAA1522 overexpression may exert its aggressiveness in metastatic patients more than in patients who received curative surgery. Further investigations involving a larger, and ideally prospective, sample set would be beneficial for corroborating these findings. Here, NHSL3 is linked to neoplasm.