In the present study, several haplotypes were found to be associated with RA risk, including HLA-DRB1*04/DRB1*03, HLA-DRB1*08/DRB1*3, HLA-DRB1*03/DRB1*03, HLA-DRB1*13/DRB1*03, and HLA-DRB1*13/DRB1*02. Here, HLA-DRB1 is linked to rheumatoid arthritis.