It is suggested to cautiously explain these results as the sample size is small.<h4>Conclusion</h4>The current meta-analysis suggested that the SNP of <i>TERT</i> (rs2736100), <i>CCDC26</i> (rs4295627), <i>CDKN2A/B</i> (rs4977756) and <i>RTEL1</i> (rs6010620) genes in glioma might increase risk of glioma, but there are ethnic differences. The gene discussed is CDKN2A; the disease is central nervous system cancer.