Our results showed that OAS1 expression in BRCA, GBM, HNSC, KIRC, LGG, LUSC, SARC, SKCM, TGCT, THCA, and UVM were positively associated with various immune checkpoint genes, such as BTLA, CD244, CD247, CD96, CSF1R, CTLA 4, IDO 1, IL 10 and LAG 3, and other immune checkpoint genes (Figure 8A). The gene discussed is BTLA; the disease is glioblastoma.