Multiple ncRNAs (e.g., miR-520a-3p, lncRNA MIR503HG, and circ_cMras) have been shown to suppress LC development by inactivating the NF-κB pathway, whereas some other ncRNAs (e.g., miR-135b and lncRNA SNHG5) can promote LC progression by enhancing the NF-κB pathway (108–112). Here, NFKB1 is linked to laryngotracheoesophageal cleft.