The serum levels of low-density-lipoprotein cholesterol (LDL-c), high-density-lipoprotein cholesterol (HDL-c), triglycerides (TG), total cholesterol (TC), Apolipoprotein B (ApoB), and Apolipoprotein A1 (ApoA1) are associated with several human diseases included cancers and are routinely used in clinical diagnosis. The gene discussed is APOB; the disease is cancer.