The number of SNPs (nSNP) in the causal relationship between serum lipid indicators and liver cancer are as follows: 22 for LDL-c, 182 for ApoB, 9 for TG, 83 for TC, 92 for HDL-c, and 267 for ApoA1 (Figure 2, Supplementary Tables 2-7). Here, APOB is linked to liver cancer.