LAMTOR5 and hepatocellular carcinoma: Finally, miR-520b can target the 3’UTR of HBXIP to inhibit its expression, while HBx can act on the complex formed by the transcription factor enhancer sp1 and survivin upstream of miR-520b to inhibit miR-520b transcription, promoting the expression of HBXIP and the proliferation of HCC cells (51).