When comparing results obtained with 50 μg/mL of hydroalcoholic extract produced from the bark of Saraca indica, which was able to increase SOD activity by 1.3-fold after exposure to X-rays (Das et al., 2015), BvFIX metabolites can be considered promising in reducing premature skin aging, since the methanolic fraction of BvFIX extract at same concentration increased SOD activity by 3.6-fold after induction of oxidative stress. This evidence concerns the gene SOD1 and aging.