PPARA and diabetes mellitus: In this sense, by producing substances with hypoglycemic activity (Azevedo et al., 2006; Frankish et al., 2010; Kumar et al., 2012; Kulkarni and Garud, 2015) and substances that activate PPARγ (Costa, 2005; Silva, 2014), Bauhinia variegata was chosen for the isolation of endophytic fungi that colonize it, to evaluate the ability of these fungi to produce metabolites that could activate PPAR (α, β/δ and, γ) and that had antioxidant activity, to search for new bioactive compounds that could be used in the treatment of diabetes.